Publications

• Age-dependent accumulation of mitochondrial tRNA mutations in mouse kidneys linked to mitochondrial kidney diseases
  Leping Zhang*, Zhe Xu*, Jia Jing*, Guoshi Chai*, Guanglei Xie, Yanfei Ru, Qunyu Lv, Xiang Zuo, Qian Zhang, Jiatong Chen, He Jin, Ning Liu, Minghua Kong, Bin Shen, Mingxi Liu, Lei Jiang, Xi Wang, Yanxiao Zhang^#, Min Jiang^#
  Nature Aging, 2025;doi:10.1038/s43587-025-00909-y
• Alternative splicing of bunched confers a dual role in hippo pathway-dependent growth and tumorigenesis
  Pengjuan Guo*, Sha Song*, Yuxiao Niu*, Xiaoyu Kuang, Dafa Zhou, Zizhang Zhou, Yanxiao Zhang^#, Xianjue Ma^#
  Oncogene, 2025;doi:10.1038/s41388-025-03348-6
• scLTdb: a comprehensive single-cell lineage tracing database
  Junyao Jiang*, Xing Ye*, Yunhui Kong*, Chenyu Guo, Mingyuan Zhang, Fang Cao, Yanxiao Zhang^#, Weike Pei^#
  Nucleic Acids Research, 2025;doi:10.1093/nar/gkae913

before 2022

• Single-cell Epigenome Analysis Reveals Age-associated Decay of Heterochromatin Domains in Excitatory Neurons in the Mouse Brain
  Yanxiao Zhang*^,#, Maria Luisa Amaral*, Chenxu Zhu, Steven F. Grieco, Xiaomeng Hou, Lin Lin, Justin Buchanan, Liqi Tong, Sebastian Preissl, Xiangmin Xu^#, Bing Ren^#
  Cell Research, 2022;doi:10.1038/s41422-022-00719-6
• An atlas of dynamic chromatin landscapes in mouse fetal development
  David U Gorkin*, Iros Barozzi*, Yuan Zhao*, Yanxiao Zhang*, Hui Huang*, Ah Young Lee, Bin Li, Joshua Chiou, Andre Wildberg, Bo Ding, Bo Zhang, Mengchi Wang, J Seth Strattan, Jean M Davidson, Yunjiang Qiu, Veena Afzal, Jennifer A Akiyama, Ingrid Plajzer-Frick, Catherine S Novak, Momoe Kato, Tyler H Garvin, Quan T Pham, Anne N Harrington, Brandon J Mannion, Elizabeth A Lee, Yoko Fukuda-Yuzawa, Yupeng He, Sebastian Preissl, Sora Chee, Jee Yun Han, Brian A Williams, Diane Trout, Henry Amrhein, Hongbo Yang, J Michael Cherry, Wei Wang, Kyle Gaulton, Joseph R Ecker, Yin Shen, Diane E Dickel, Axel Visel^#, Len A Pennacchio^#, Bing Ren^#
  Nature, 2020;doi:10.1038/s41586-020-2093-3
• Transcriptionally active HERV-H retrotransposons demarcate topologically associating domains in human pluripotent stem cells
  Yanxiao Zhang*, Ting Li*, Sebastian Preissl*, Maria Luisa Amaral, Jonathan D. Grinstein, Elie N. Farah, Eugin Destici, Yunjiang Qiu, Rong Hu, Ah Young Lee, Sora Chee, Kaiyue Ma, Zhen Ye, Quan Zhu, Hui Huang, Rongxin Fang, Leqian Yu, Juan Carlos Izpisua Belmonte, Jun Wu, Sylvia M. Evans, Neil C. Chi^#, Bing Ren^#
  Nature Genetics, 2019;doi:10.1038/s41588-019-0479-7
• Genomic binding of PAX8-PPARG fusion protein regulates cancer-related pathways and alters the immune landscape of thyroid cancer
  Yanxiao Zhang, Jingcheng Yu, Vladimir Grachtchouk, Tingting Qin, Carey N Lumeng, Maureen A Sartor, Ronald J Koenig
  Oncotarget, 2017;doi:10.18632/oncotarget.14050
• Subtypes of HPV-positive head and neck cancers are associated with HPV characteristics, copy number alterations, PIK3CA mutation, and pathway signatures
  Yanxiao Zhang, Lada A Koneva, Shama Virani, Anna E Arthur, Alisha Virani, Pelle B Hall, Charles D Warden, Thomas E Carey, Douglas B Chepeha, Mark E Prince, Jonathan B McHugh, Gregory T Wolf, Laura S Rozek, Maureen A Sartor
  Clinical Cancer Research, 2016;doi:10.1158/1078-0432.CCR-16-0323
• Genomic binding and regulation of gene expression by the thyroid carcinoma-associated PAX8-PPARG fusion protein
  Yanxiao Zhang, Jingcheng Yu, Chee Lee, Bin Xu, Maureen A Sartor, Ronald J Koenig
  Oncotarget, 2015;doi:10.18632/oncotarget.6340
• PePr: a peak-calling prioritization pipeline to identify consistent or differential peaks from replicated ChIP-Seq data
  Yanxiao Zhang*, Yu-Hsuan Lin*, Timothy D Johnson, Laura S Rozek, Maureen A Sartor
  Bioinformatics, 2014;doi:10.1093/bioinformatics/btu372